![]() ![]() These data are all available to search or download through NetwoRx users can search by drug name, gene name or gene set identifier. In addition, we applied data-mining approaches to identify yeast pathways, functions and phenotypes that are targeted by particular drugs, compute measures of drug–drug similarity and construct drug–phenotype networks. In total, NetwoRx stores data on 5924 genes and 466 drugs. ![]() NetwoRx ( ) is the first resource to store data from these extremely valuable yeast chemogenomics experiments. But a high-throughput assay unique to yeast-barcode-based chemogenomic screens-can measure the individual drug response of every yeast deletion mutant in parallel. The set of known drug targets is widely acknowledged to be biased and incomplete, and so gives only limited insight into the system-wide effects of drugs. Drug modes of action are complex and still poorly understood. ![]()
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